Robert "Fish" Fishman once was the extremely dedicated and astoundingly passionate drummer for the eighties hair band Vesuvius. He was living the rock 'n' roll dream until he was unceremoniously kicked out of the band. Twenty years after his rock star fantasies were destroyed, just when Fish has finally given up all hope, he hears that his nephew's high school rock band A.D.D. is looking for a new drummer. Reluctantly, they let him join the group, giving him a chance to reclaim the rock God throne he's always thought he deserved. As he pursues his dream, he takes the young band along for the ride of their lives.

Henry Poole just wants to disappear. Shattered by circumstances beyond his control, he buys a cookie-cutter house in a drab, middle-class, L.A. neighborhood and settles in with case of vodka and all the junk food he can eat. But, Henry's self-imposed exile is shattered when his neighbor, Esperanza, discovers a mysterious stain on Henry's stucco wall that is seen to have miraculous powers. She begins leading pilgrimages to the "holy site" and invites church officials to inspect the apparition. Although Henry remains skeptical, he finds himself gradually drawn back towards life, especially when his friendship with another neighbor, eight-year-old Millie, brings him closer to her beautiful single mother, Dawn.